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Steroids, including orally available forms, are associated with side effects, especially if the drugs are used for an extended period of time. Oral steroids can cause weight gain, appetite changes, irritability, fluid retention, weight gain, glaucoma, high blood pressure, susceptibility to infections, and bone loss. You can read on powerbulks more about anabolic steroids effects. Patients who need to take oral steroids in the long term must be closely monitored so that side effects can be identified and treated.